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  • Writer's pictureNancy Mullan, MD

MTHFR + and Covid-19

The best defense against the Covid-19 virus, besides the physical measures that we all have heard so much about, is to have a primed and ready immune system. This takes methyl groups. Methyl groups in themselves are anti-viral. When a methyl group attaches to the appropriate receptor site on a virus, it silences the virus. It makes the virus unable to infect your cells. So it is worthwhile right now to be sure that your ability to make methyl groups is primed and functioning. When you have an MTHFR C677T mutation, your ability to make methyl groups is diminished. If you know about the other mutations in your methyl group forming pathway, you can supplement around the blocks and get the methyl groups you need. If you don't know about the other mutations in your methyl group forming pathway, you can still do this, but perhaps less well. And, in either case, you can supplement methyl groups with the well known 5-methyl folate and other methyl donating supplements.  In order to get your methyl group forming pathway working, you need folate and B12 inside of your cell, not just in your blood stream. This is where lithium comes in. Lithium enhances the uptake of folate and B12 into the cell. So you want to make sure that you have enough lithium in your body. Many people with MTHFR mutations are low in lithium. A really reliable measurement of lithium levels comes through testing with a Hair Elements Analysis and balancing those results agains a Urine Essential Elements test. Hair elements gives you a three month average of lithium levels and the urine test gives you the amount of lithium that you excreted on the day you took the test. Between the two tests, you can really tell what your lithium levels are. If you are MTHFR + and you are in one of the demographic areas that are hardest hit, you can do more than wash your hands and stay inside. You can dose up on Vitamin C which has well known anti viral properties. You can make sure you are also taking Vitamins A and D so your levels of these important immune boosters do not get low. You can do this no matter what you think you may be coming down with.

Finally, if you do get infected with the Covid-19 virus, if you are sick enough, you will have to go to a hospital. There you get the standard treatment. You can also ask for/demand that you be treated with chloroquine/hydroxychloroquine and Azithromycin. Do not get involved with who mentioned this first or if it is an off label use, just get it. There is another anti viral, Remdesivir, for people whose symptoms are more progressed. If you think you have this virus, do not delay getting tested and treated. It can exacerbate quickly. Within 24 hours you can go from feeling flu-like to needing an ICU.... If you have been told that you have the virus but you can ride it out at home, don't try that if you are MTHFR +. Mainstream doctors don't think about this mutation and its profoundly immune inhibiting propensities. Find a local naturopathic doctor and get high dose IV Vitamin C at minimum. The doctor may also offer IV Hydrogen Peroxide and or Ozone and he can give you appropriate vitamin infusions for your situation. Jump on this infection with two feet. If you have any questions about how well you are making methyl groups or you would like a tune up of that function, you can get time with me. All of my appointments are virtual at this point, of course. If you have never consulted me before and you want expert help personalized to your genetics and your own particular biochemistry, you can get an Exploratory Conversation with me. I offer this service so that you can ask any questions you may have about Covid-19 and your situation. This is a 30-minute conversation in which I listen to your health issues, review what test results you have, and make recommendations about what I think would optimize your capacity to make methyl groups and your immunity.  The fee for this service is $129. It is easy to set a time for this conversation, and it may save you from getting sick with anything, not just Covid-19. You may be talking with a clinician who doesn’t know anything about the genetics or molecular biology of MTHFR+ or of its impact on your ability to fight infection. You are dealing with conditions in your body that are outside of the norm. I can give you clarifying input that gives you stronger disease fighting potential. I have a free, downloadable ebook at with additional detail about methylation issues. Click here to download. I want to help you strengthen your immunity right now. Take care, Dr. Mullan

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What people are saying about my work: 

I shudder at the thought of what my family would be like without Dr. Mullan. Thankfully, with her help, we have stopped my husband's chronic 30 year battle with kidney stones. He is no longer forming them and is stone free. My thyroid is now working normally, my body temperature is almost normal and my hair has grown back. My oldest daughter's Autism is in the process of being reversed and her hair pulling has stopped. The greatest blessing from our good health is the birth of my second daughter Ava, now one-year-old. At 50 years old I carried her to term.  One of my doctors commented to me saying “ you are carrying this baby like a 22-year-old.” Yes, I am because of Dr. Mullan and working on my methylation pathway.  One by one she is knocking off symptoms and bringing us back to health. The future is bright! Thank you, Dr. Mullan, for the work you do.   - JVW Wow.  I feel great.  Thank you for your help.  It’s amazing really.  Like a light turned on.  Curious to see what the next tests show.   To ride this peak indefinitely is my goal.  Ha.  I have energy again.  Yay!  Really grateful. - DG I am so relieved. My daughter is doing SO WELL since we started with you!  We have been to so many doctors and tried so many things.  Now I can start working on my own program with you.... - GV So excellent!  I literally learn something with every single post and I get clarification on things that have been lingering on my mind… - VB You are giving people a huge gift by empowering them…It’s about helping the patient become their own healer by taking them to a higher level of consciousness… - AL Thank you so much, Dr. Mullan.  Thank you so, so much for everything you do. - MS Wow!  I have to tell you, it’s so nice to hear good news especially about a child.  Anxiety, OCD and a host of other mental/psychiatric symptoms have been a huge hurdle for me.  So to hear this story of all those awful symptoms totally going away is such a bright light for me!!!! - TR Fantastic, caring, smart, savvy doc.  I worked with Dr. Mullan for a couple of years to help MTHFR mutations and their associating expressions!  To say the least!  She's brilliant.  At that time she had weekly calls for her patients - free - where we could ask questions and she would reply.  What doctors do this?  She does.  She's also an animal lover and is right on about the way she practices medicine.  I highly recommend her.  In good health! - MG You're in good hands with Dr. Mullan. She is intelligent, caring and knowledgable, spending much time with you. She thinks outside the box to achieve wellness for you. She really knows what's going on inside your body. - MS Dr. Nancy Mullan is a beautiful person. She is an expert in her field and has helped our family so much. I am very grateful to her.  She came highly recommended and I know why. I would recommend her and her website for information re: healing from a genetic point of view. Thank you, Dr. Mullan, for everything. - GD Dr. Mullan has helped me with issues that I have struggled with for years.  She is knowledgable and practical.  I would recommend her to others. - BC

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May 18, 2020

I have a double mutation in my MTHFR gene. I'm I at higher risk of getting COVID? I'm at a higher risk of getting more ill if I do contract the virus?

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